Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ndkNucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (145 aa)    
Predicted Functional Partners:
rps10
30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
  
 0.989
rps7
30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family.
  
 0.989
rps12
30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.
  
 0.989
rpl24e
50S ribosomal protein L24; Binds to the 23S rRNA.
  
    0.988
rps2
30S ribosomal protein S2; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS2 family.
  
 0.987
rps15
30S ribosomal protein S15; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  0.987
rps11
30S ribosomal protein S11; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family.
  
 0.985
rps5
30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy.
  
 0.974
rps28e
30S ribosomal protein S28e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eS28 family.
  
   0.968
rps14P
30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles.
  
 0.964
Your Current Organism:
Acidianus manzaensis
NCBI taxonomy Id: 282676
Other names: A. manzaensis, NBRC 100595, strain NA-1
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