Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ARM75921.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (483 aa)    
Predicted Functional Partners:
ARM75925.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.664
ARM75922.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.652
ARM75923.1
Catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate and the decarboxylation of 3-methylmalate to 2-oxobutyrate and of D-malate to pyruvate; involved in leucine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.593
ARM75011.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.589
ARM75826.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.580
ARM75126.1
4Fe-4S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.574
ARM75089.1
Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.563
proS
proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
       0.559
B6F84_03610
Transposase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.533
ileS
isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
       0.532
Your Current Organism:
Acidianus manzaensis
NCBI taxonomy Id: 282676
Other names: A. manzaensis, NBRC 100595, strain NA-1
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