Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
ARM75976.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (179 aa)    
Predicted Functional Partners:
ARM75977.1
AMMECR1 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.949
ARM75975.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.839
ARM75978.1
Glutaredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.824
ARM75974.1
RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.815
ARM75972.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.613
ARM75979.1
CopG family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.602
ARM76024.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.559
ARM75973.1
Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.556
pelA
mRNA surveillance protein pelota; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
       0.487
nfi
Endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
 
     0.420
Your Current Organism:
Acidianus manzaensis
NCBI taxonomy Id: 282676
Other names: A. manzaensis, NBRC 100595, strain NA-1
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