Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
ARM76191.1Lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa)    
Predicted Functional Partners:
ARM74798.1
Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LDH/MDH superfamily.
    
 0.927
ARM77082.1
Mannonate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.749
ARM75958.1
Acetate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.618
ARM76709.1
Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family.
     
 0.563
ARM77070.1
Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.538
ARM75447.1
GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.440
ARM74627.1
Biotin--protein ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.425
ARM76518.1
3-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
  
 0.425
ARM75765.1
DNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.414
Your Current Organism:
Acidianus manzaensis
NCBI taxonomy Id: 282676
Other names: A. manzaensis, NBRC 100595, strain NA-1
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