Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
oggDNA lyase; Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites); Belongs to the type-2 OGG1 family. (202 aa)    
Predicted Functional Partners:
ARM76520.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.949
ARM77172.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.581
ARM76517.1
Hydrogenase expression protein HypE; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.576
ARM76521.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.529
ARM76515.1
DNA topoisomerase I; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.517
ARM76518.1
3-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
       0.502
rpoK
DNA-directed RNA polymerase subunit K; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family.
       0.443
Your Current Organism:
Acidianus manzaensis
NCBI taxonomy Id: 282676
Other names: A. manzaensis, NBRC 100595, strain NA-1
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