Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ARM76778.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (349 aa)    
Predicted Functional Partners:
gcvH-3
Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 
 0.752
gcvH-2
Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 
 0.741
ARM74627.1
Biotin--protein ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.735
gcvH
Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
   
 0.700
ARM76780.1
Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.690
ARM76781.1
Biotin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.689
ARM74899.1
Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
  
 0.601
ARM76272.1
Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.589
ARM74655.1
Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.578
ARM76763.1
Pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
  
 0.574
Your Current Organism:
Acidianus manzaensis
NCBI taxonomy Id: 282676
Other names: A. manzaensis, NBRC 100595, strain NA-1
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