Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARM76868.1Response regulator SirA; Derived by automated computational analysis using gene prediction method: Protein Homology. (83 aa)    
Predicted Functional Partners:
ARM76869.1
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.975
ARM76867.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.939
B6F84_13130
Hypothetical protein; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.714
ARM76862.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.544
ARM75326.1
Sulfur reduction protein DsrP; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.469
ARM75128.1
Molybdenum cofactor biosynthesis protein MoaD; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.442
ARM76667.1
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.437
thiI
tRNA 4-thiouridine(8) synthase ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
  
 0.422
ARM76165.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.406
ARM76765.1
Peroxiredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.406
Your Current Organism:
Acidianus manzaensis
NCBI taxonomy Id: 282676
Other names: A. manzaensis, NBRC 100595, strain NA-1
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.