NPC1 protein (Anolis carolinensis) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

NPC1

NPC intracellular cholesterol transporter 1. (1282 aa)

Predicted Functional Partners:

NPC2

0.998

SREBF1

0.858

SREBF2

0.858

MYCN

0.784

INSIG2

0.664

INSIG1

0.664

ANKRD29

0.640

SLC38A9

0.627

LAMP1

0.588

EPHA2

0.571

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKRD29	NPC1	ENSACAP00000000270	ENSACAP00000000255	Ankyrin repeat domain 29.	NPC intracellular cholesterol transporter 1.	0.640
EPHA2	NPC1	ENSACAP00000006222	ENSACAP00000000255	EPH receptor A2.	NPC intracellular cholesterol transporter 1.	0.571
INSIG1	NPC1	ENSACAP00000010764	ENSACAP00000000255	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	NPC intracellular cholesterol transporter 1.	0.664
INSIG1	SREBF2	ENSACAP00000010764	ENSACAP00000004254	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	Sterol regulatory element binding transcription factor 2.	0.738
INSIG2	NPC1	ENSACAP00000001681	ENSACAP00000000255	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	NPC intracellular cholesterol transporter 1.	0.664
INSIG2	SREBF2	ENSACAP00000001681	ENSACAP00000004254	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	Sterol regulatory element binding transcription factor 2.	0.636
LAMP1	NPC1	ENSACAP00000000241	ENSACAP00000000255	Lysosomal associated membrane protein 1.	NPC intracellular cholesterol transporter 1.	0.588
MYCN	NPC1	ENSACAP00000011139	ENSACAP00000000255	MYCN proto-oncogene, bHLH transcription factor.	NPC intracellular cholesterol transporter 1.	0.784
NPC1	ANKRD29	ENSACAP00000000255	ENSACAP00000000270	NPC intracellular cholesterol transporter 1.	Ankyrin repeat domain 29.	0.640
NPC1	EPHA2	ENSACAP00000000255	ENSACAP00000006222	NPC intracellular cholesterol transporter 1.	EPH receptor A2.	0.571
NPC1	INSIG1	ENSACAP00000000255	ENSACAP00000010764	NPC intracellular cholesterol transporter 1.	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	0.664
NPC1	INSIG2	ENSACAP00000000255	ENSACAP00000001681	NPC intracellular cholesterol transporter 1.	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	0.664
NPC1	LAMP1	ENSACAP00000000255	ENSACAP00000000241	NPC intracellular cholesterol transporter 1.	Lysosomal associated membrane protein 1.	0.588
NPC1	MYCN	ENSACAP00000000255	ENSACAP00000011139	NPC intracellular cholesterol transporter 1.	MYCN proto-oncogene, bHLH transcription factor.	0.784
NPC1	NPC2	ENSACAP00000000255	ENSACAP00000016203	NPC intracellular cholesterol transporter 1.	NPC intracellular cholesterol transporter 2.	0.998
NPC1	SLC38A9	ENSACAP00000000255	ENSACAP00000014822	NPC intracellular cholesterol transporter 1.	Solute carrier family 38 member 9.	0.627
NPC1	SREBF1	ENSACAP00000000255	ENSACAP00000001306	NPC intracellular cholesterol transporter 1.	Sterol regulatory element binding transcription factor 1.	0.858
NPC1	SREBF2	ENSACAP00000000255	ENSACAP00000004254	NPC intracellular cholesterol transporter 1.	Sterol regulatory element binding transcription factor 2.	0.858
NPC2	NPC1	ENSACAP00000016203	ENSACAP00000000255	NPC intracellular cholesterol transporter 2.	NPC intracellular cholesterol transporter 1.	0.998
SLC38A9	NPC1	ENSACAP00000014822	ENSACAP00000000255	Solute carrier family 38 member 9.	NPC intracellular cholesterol transporter 1.	0.627