Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TBX22T-box transcription factor 22. (400 aa)    
Predicted Functional Partners:
TBX2
T-box transcription factor 2.
 
      0.786
CLPP
ATP-dependent Clp protease proteolytic subunit.
      
 0.762
CLPX
Caseinolytic mitochondrial matrix peptidase chaperone subunit.
      
 0.675
MEOX2
Mesenchyme homeobox 2.
    
 
 0.640
MSX1
Msh homeobox 1.
    
 
 0.629
SEBOX
SEBOX homeobox.
    
 0.603
znf280d
C2H2-type domain-containing protein.
      
 0.603
CLPB
ClpB homolog, mitochondrial AAA ATPase chaperonin.
      
 0.582
SHOX2
Short stature homeobox 2.
    
 0.574
CETP
Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
      
 0.571
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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