Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISCUIron-sulfur cluster assembly enzyme. (96 aa)    
Predicted Functional Partners:
nfs1
Aminotran_5 domain-containing protein.
 
 0.999
FXN
Frataxin.
    
 0.998
lyrm4
Uncharacterized protein; Belongs to the complex I LYR family.
    
 0.997
SCLY
Selenocysteine lyase.
  
 0.977
ISCA2
Iron-sulfur cluster assembly 2.
  
 
 0.963
mocos
MOSC domain-containing protein.
  
 0.958
HSPA9
Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family.
  
 0.958
LOC103281780
Aminotran_5 domain-containing protein.
  
 0.958
ISCA1
Iron-sulfur cluster assembly 1.
  
 
 0.944
FDX1
Ferredoxin 1.
 
 0.940
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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