STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PARD3Par-3 family cell polarity regulator. (1327 aa)    
Predicted Functional Partners:
PRKCI
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
    
 0.997
PARD6A
Par-6 family cell polarity regulator alpha.
    
 0.976
JAM3
Junctional adhesion molecule 3.
    
 0.936
Nectin1
Uncharacterized protein.
    
 0.930
TIAM1
T cell lymphoma invasion and metastasis 1.
    
 0.930
PATJ
PATJ crumbs cell polarity complex component.
    
0.924
NECTIN3
Nectin cell adhesion molecule 3.
   
 0.913
OCLN
Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family.
    
 0.904
F2R
Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family.
    
  0.901
F2RL2
Coagulation factor II thrombin receptor like 2.
    
  0.901
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.