Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NEUROG1Neurogenin 1. (228 aa)    
Predicted Functional Partners:
INSM1
INSM transcriptional repressor 1.
   
 0.769
PAX6
Paired box 6.
   
 0.753
NKX2-2
NK2 homeobox 2.
   
 0.605
PCSK2
Proprotein convertase subtilisin/kexin type 2; Belongs to the peptidase S8 family.
   
  
 0.596
TCF4
Transcription factor 4.
    
 
 0.548
TCF12
Transcription factor 12.
    
 
 0.548
LOC103282379
Transcription factor 3.
    
 
 0.548
LOC100563897
BHLH domain-containing protein.
    
 
 0.548
HES6
Hes family bHLH transcription factor 6.
    
 0.535
ins
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
 
 0.518
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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