CHAF1A protein (Anolis carolinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

CHAF1A

Chromatin assembly factor 1 subunit A. (700 aa)

Predicted Functional Partners:

CHAF1B

0.985

rbbp4

0.894

MCM5

0.855

MCM2

0.833

ASF1B

0.831

MCM3

0.815

WDR73

0.773

POLA1

0.766

PCNA

0.764

ASF1A

0.748

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASF1A	ASF1B	ENSACAP00000017422	ENSACAP00000012018	Anti-silencing function 1A histone chaperone.	Anti-silencing function 1B histone chaperone.	0.526
ASF1A	CHAF1A	ENSACAP00000017422	ENSACAP00000001287	Anti-silencing function 1A histone chaperone.	Chromatin assembly factor 1 subunit A.	0.748
ASF1A	CHAF1B	ENSACAP00000017422	ENSACAP00000012495	Anti-silencing function 1A histone chaperone.	Chromatin assembly factor 1 subunit B.	0.924
ASF1A	MCM2	ENSACAP00000017422	ENSACAP00000007325	Anti-silencing function 1A histone chaperone.	DNA helicase; Belongs to the MCM family.	0.956
ASF1A	MCM3	ENSACAP00000017422	ENSACAP00000005109	Anti-silencing function 1A histone chaperone.	DNA helicase; Belongs to the MCM family.	0.409
ASF1A	MCM5	ENSACAP00000017422	ENSACAP00000016374	Anti-silencing function 1A histone chaperone.	DNA helicase; Belongs to the MCM family.	0.550
ASF1A	PCNA	ENSACAP00000017422	ENSACAP00000000398	Anti-silencing function 1A histone chaperone.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.427
ASF1A	WDR73	ENSACAP00000017422	ENSACAP00000015677	Anti-silencing function 1A histone chaperone.	WD repeat domain 73.	0.663
ASF1A	rbbp4	ENSACAP00000017422	ENSACAP00000003318	Anti-silencing function 1A histone chaperone.	RB binding protein 4, chromatin remodeling factor.	0.834
ASF1B	ASF1A	ENSACAP00000012018	ENSACAP00000017422	Anti-silencing function 1B histone chaperone.	Anti-silencing function 1A histone chaperone.	0.526
ASF1B	CHAF1A	ENSACAP00000012018	ENSACAP00000001287	Anti-silencing function 1B histone chaperone.	Chromatin assembly factor 1 subunit A.	0.831
ASF1B	CHAF1B	ENSACAP00000012018	ENSACAP00000012495	Anti-silencing function 1B histone chaperone.	Chromatin assembly factor 1 subunit B.	0.929
ASF1B	MCM2	ENSACAP00000012018	ENSACAP00000007325	Anti-silencing function 1B histone chaperone.	DNA helicase; Belongs to the MCM family.	0.953
ASF1B	MCM3	ENSACAP00000012018	ENSACAP00000005109	Anti-silencing function 1B histone chaperone.	DNA helicase; Belongs to the MCM family.	0.612
ASF1B	MCM5	ENSACAP00000012018	ENSACAP00000016374	Anti-silencing function 1B histone chaperone.	DNA helicase; Belongs to the MCM family.	0.611
ASF1B	PCNA	ENSACAP00000012018	ENSACAP00000000398	Anti-silencing function 1B histone chaperone.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.427
ASF1B	WDR73	ENSACAP00000012018	ENSACAP00000015677	Anti-silencing function 1B histone chaperone.	WD repeat domain 73.	0.663
ASF1B	rbbp4	ENSACAP00000012018	ENSACAP00000003318	Anti-silencing function 1B histone chaperone.	RB binding protein 4, chromatin remodeling factor.	0.834
CHAF1A	ASF1A	ENSACAP00000001287	ENSACAP00000017422	Chromatin assembly factor 1 subunit A.	Anti-silencing function 1A histone chaperone.	0.748
CHAF1A	ASF1B	ENSACAP00000001287	ENSACAP00000012018	Chromatin assembly factor 1 subunit A.	Anti-silencing function 1B histone chaperone.	0.831