STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FARP2FERM, ARH/RhoGEF and pleckstrin domain protein 2. (1064 aa)    
Predicted Functional Partners:
CDC42
Uncharacterized protein.
    
 0.939
SRC
Tyrosine-protein kinase.
     
  0.923
PIP5K1A
Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha.
     
 0.703
NRP1
Neuropilin; Belongs to the neuropilin family.
     
 0.690
PIP5K1B
Phosphatidylinositol-4-phosphate 5-kinase type 1 beta.
     
 0.576
cfap99
Uncharacterized protein.
      
 0.543
RND1
Rho family GTPase 1.
    
 0.513
SEMA3B
Semaphorin 3B; Belongs to the semaphorin family.
     
 0.509
SEMA3A
Semaphorin 3A; Belongs to the semaphorin family.
     
 0.509
DOCK3
Dedicator of cytokinesis 3; Belongs to the DOCK family.
     
 0.489
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.