Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ARHGAP6Rho GTPase activating protein 6. (531 aa)    
Predicted Functional Partners:
G1KVJ2_ANOCA
Uncharacterized protein.
 
     0.929
HCCS
Cytochrome c heme lyase; Links covalently the heme group to the apoprotein of cytochrome c.
      
 0.839
UNC50
Unc-50 inner nuclear membrane RNA binding protein.
      
 0.731
HERC2
HECT and RLD domain containing E3 ubiquitin protein ligase 2.
      
 0.691
AKAP17A
A-kinase anchoring protein 17A.
      
 0.614
DCTD
dCMP deaminase.
      
 0.608
RAP2A
RAP2A, member of RAS oncogene family.
    
 0.607
ASPM
Abnormal spindle microtubule assembly.
   
 
 0.583
KIF11
Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
  
 0.574
UXS1
UDP-glucuronate decarboxylase 1.
      
 0.571
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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