Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100551550Interleukin-1. (184 aa)    
Predicted Functional Partners:
IL1R1
Interleukin 1 receptor type 1.
    
 0.957
IL1RAP
Interleukin 1 receptor accessory protein.
     
 0.939
IL1R2
Interleukin 1 receptor type 2.
     
 0.915
IL6
Interleukin 6.
   
  
 0.505
ifnar2
Uncharacterized protein.
      
 0.460
IL1RL1
Interleukin 1 receptor like 1.
    
 0.426
NFKBIZ
NFKB inhibitor zeta.
      
 0.411
CHST2
Sulfotransferase; Belongs to the sulfotransferase 1 family.
      
 0.409
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.