Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DDX58DExD/H-box helicase 58. (922 aa)    
Predicted Functional Partners:
SMC5
Structural maintenance of chromosomes 5.
   
 
 0.759
isg15
Uncharacterized protein.
   
 0.756
FANCL
FA complementation group L.
    
 0.735
FANCG
FA complementation group G.
    
 0.720
FANCF
FA complementation group F.
    
 0.707
SMC6
Structural maintenance of chromosomes 6.
   
 
 0.704
MSH6
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
   
 
 0.702
FANCB
FA complementation group B.
   
 0.697
FANCC
FA complementation group C.
    
 0.697
R3HDM2
Uncharacterized protein.
      
 0.694
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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