Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FGD3FYVE, RhoGEF and PH domain containing 3. (677 aa)    
Predicted Functional Partners:
CDC42
Uncharacterized protein.
   
 0.967
FGD1
FYVE, RhoGEF and PH domain containing 1.
     
0.904
FGD4
FYVE, RhoGEF and PH domain containing 4.
    
 0.577
ARHGEF11
Rho guanine nucleotide exchange factor 11.
    
0.574
ARHGEF33
Rho guanine nucleotide exchange factor 33.
     
 0.572
speg
Uncharacterized protein.
     
 0.567
ITSN2
Intersectin 2.
     
 0.489
ITSN1
Intersectin 1.
     
 0.457
ARHGEF15
Rho guanine nucleotide exchange factor 15.
    
0.435
DOCK8
Dedicator of cytokinesis 8; Belongs to the DOCK family.
   
 
 0.432
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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