Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FAM3BFamily with sequence similarity 3 member B. (236 aa)    
Predicted Functional Partners:
METTL23
Methyltransferase like 23.
      
 0.581
RIPK4
Receptor interacting serine/threonine kinase 4.
      
 0.571
BACE2
Beta-secretase 2; Belongs to the peptidase A1 family.
 
    
 0.551
CMSS1
Cms1 ribosomal small subunit homolog.
      
 0.483
H9GKW1_ANOCA
Uncharacterized protein.
      
 0.480
BACE1
Beta-secretase 1; Belongs to the peptidase A1 family.
 
    
 0.404
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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