Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SMPDL3AAcid sphingomyelinase-like phosphodiesterase. (455 aa)    
Predicted Functional Partners:
sqor
Uncharacterized protein.
      
 0.709
ZNF330
Zinc finger protein 330.
      
 0.677
RBM48
RNA binding motif protein 48.
      
 0.666
Fam227a
Uncharacterized protein.
      
 0.614
BTBD10
BTB domain containing 10.
      
 0.606
KCTD20
Potassium channel tetramerization domain containing 20.
      
 0.606
LYSMD2
LysM domain containing 2.
      
 0.597
ttc9c
TPR_REGION domain-containing protein.
      
 0.595
Togaram2
TOG domain-containing protein.
      
 0.583
LOC100557138
Uncharacterized protein; Belongs to the GST superfamily.
      
 0.574
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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