STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1282 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
   
 0.998
EGFR
Receptor protein-tyrosine kinase.
    
 0.972
KRAS
KRAS proto-oncogene, GTPase.
   
 0.959
NRAS
NRAS proto-oncogene, GTPase.
   
 0.955
HRAS
HRas proto-oncogene, GTPase.
   
 0.955
LOC100559807
Uncharacterized protein.
   
 0.955
FGFR2
Fibroblast growth factor receptor.
    
 0.945
MRAS
Muscle RAS oncogene homolog.
    
 0.938
FGFR4
Fibroblast growth factor receptor.
    
 0.937
RRAS2
RAS related 2.
   
 0.936
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.