Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1282 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
    
 0.999
EGFR
Receptor protein-tyrosine kinase.
    
 0.972
NRAS
NRAS proto-oncogene, GTPase.
   
 0.965
HRAS
HRas proto-oncogene, GTPase.
   
 0.965
KRAS
KRAS proto-oncogene, GTPase.
   
 0.965
LOC100559807
Uncharacterized protein.
   
 0.965
FGFR1
Fibroblast growth factor receptor.
    
 0.953
FGFR2
Fibroblast growth factor receptor.
    
 0.953
FGFR4
Fibroblast growth factor receptor.
    
 0.952
MRAS
Muscle RAS oncogene homolog.
    
 0.949
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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