STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CASP10Caspase 10; Belongs to the peptidase C14A family. (528 aa)    
Predicted Functional Partners:
Fadd
Death domain-containing protein.
   
 0.998
CFLAR
CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family.
   
0.997
TRADD
TNFRSF1A associated via death domain.
    
 0.991
RIPK1
Receptor interacting serine/threonine kinase 1.
   
 0.990
Bid
BH3-interacting domain death agonist; Counters the protective effect of Bcl-2.
   
 0.984
FAS
Fas cell surface death receptor.
   
 0.975
tnfrsf10b
Uncharacterized protein.
    
 0.932
LOC103282606
Protein kinase domain-containing protein.
   
 0.929
H9GUF0_ANOCA
Protein kinase domain-containing protein.
   
 0.929
FASLG
Fas ligand; Belongs to the tumor necrosis factor family.
   
 0.908
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.