Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
amdhd2N-acetylglucosamine-6-phosphate deacetylase; Belongs to the metallo-dependent hydrolases superfamily. NagA family. (383 aa)    
Predicted Functional Partners:
GNPDA2
Glucosamine-6-phosphate isomerase.
 0.999
GNPDA1
Glucosamine-6-phosphate isomerase.
 0.999
GFPT2
Glutamine-fructose-6-phosphate transaminase 2.
    
 0.990
PGM3
Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O- glycosylation; Belongs to the phosphohexose mutase family.
    
 0.973
NAGK
N-acetylglucosamine kinase.
  
 
 0.967
GNPNAT1
Glucosamine 6-phosphate N-acetyltransferase.
    
 0.931
HK2
Hexokinase 2.
   
 
 0.928
HK3
Hexokinase 3.
   
 
 0.928
HKDC1
Hexokinase domain containing 1.
   
 
 0.928
H6PD
Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase.
  
 0.918
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.