Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
UBE2L3Ubiquitin conjugating enzyme E2 L3; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)    
Predicted Functional Partners:
ARIH1
RBR-type E3 ubiquitin transferase.
    
 0.982
UBE3A
Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
    
 0.982
Park2
RBR-type E3 ubiquitin transferase.
    
 0.978
rnf31
Uncharacterized protein.
   
 0.978
WWP1
E3 ubiquitin-protein ligase.
    
 0.975
RBX1
Ring-box 1.
   
 0.971
rps27a
Ubiquitin-like domain-containing protein.
   
 0.970
HACE1
HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1.
    
 0.970
ARIH2
RBR-type E3 ubiquitin transferase.
   
 0.967
UBA52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
 0.966
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
Server load: low (18%) [HD]