Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DCTN5Dynactin subunit 5. (185 aa)    
Predicted Functional Partners:
DCTN4
Dynactin subunit 4.
    
 0.999
DCTN6
Dynactin subunit 6.
   
 0.998
ACTR10
Actin related protein 10; Belongs to the actin family.
    
 0.993
DCTN2
Dynactin subunit 2.
    
 0.992
dctn1
CAP-Gly domain-containing protein.
    
 0.988
DYNC1H1
Dynein cytoplasmic 1 heavy chain 1.
   
 0.956
H9GCW8_ANOCA
Uncharacterized protein.
    
 0.947
DYNC1LI2
Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
    
 0.916
PDGFD
Platelet derived growth factor D.
    
   0.912
CSPP1
Centrosome and spindle pole associated protein 1.
    
   0.898
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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