Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tmeff1Uncharacterized protein. (374 aa)    
Predicted Functional Partners:
alg1
Glycos_transf_1 domain-containing protein.
      
 0.696
MSANTD3
Myb/SANT DNA binding domain containing 3.
 
      0.667
cog2
DUF3510 domain-containing protein.
      
 0.546
ZDHHC5
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
    
   0.501
ZDHHC8
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
    
   0.501
AACS
Acetoacetyl-CoA synthetase.
      
 0.497
TSC1
TSC complex subunit 1.
      
 0.460
PPIP5K2
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...]
      
 0.460
RETREG3
Reticulophagy regulator family member 3.
      
 0.460
TLK1
Tousled like kinase 1.
      
 0.433
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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