Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PYCR3Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (276 aa)    
Predicted Functional Partners:
pycr1
Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.
  
 
 
0.988
LOC100554382
Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.
   
 0.948
P4HA1
Prolyl 4-hydroxylase subunit alpha 1.
     
 0.932
P4HA2
Prolyl 4-hydroxylase subunit alpha 2.
     
 0.931
P4HA3
Prolyl 4-hydroxylase subunit alpha 3.
     
 0.929
LAP3
Leucine aminopeptidase 3.
    
 0.923
ALDH18A1
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
 
 
 0.877
dao
DAO domain-containing protein.
  
 
 0.827
OAT
Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
  
 0.768
L3HYPDH
Trans-L-3-hydroxyproline dehydratase.
    
 0.758
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.