Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1041 aa)    
Predicted Functional Partners:
ITGB5
Integrin beta; Belongs to the integrin beta chain family.
   
 0.999
ITGB8
Integrin beta; Belongs to the integrin beta chain family.
    
 0.999
ITGB6
Integrin beta; Belongs to the integrin beta chain family.
   
 0.999
itgb3
Integrin beta; Belongs to the integrin beta chain family.
   
 0.999
FN1
Fibronectin 1.
    
 0.996
vtn
SMB domain-containing protein.
   
 0.992
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
   
 0.981
SPP1
Secreted phosphoprotein 1.
   
 0.975
TGFB1
Transforming growth factor beta; Belongs to the TGF-beta family.
   
 0.956
THBS2
Thrombospondin 2.
   
 0.947
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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