STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORAI1ORAI calcium release-activated calcium modulator 1. (226 aa)    
Predicted Functional Partners:
STIM1
Stromal interaction molecule 1.
    
 0.997
STIM2
Stromal interaction molecule 2.
    
 0.993
ORAI3
ORAI calcium release-activated calcium modulator 2.
  
 
0.966
TRPC1
Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family.
    
 
 0.790
PYROXD1
Pyridine nucleotide-disulphide oxidoreductase domain 1.
 
      0.768
NFAT5
Nuclear factor of activated T cells 5.
   
  
 0.446
CAV1
Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.
      
 0.434
SARAF
Store-operated calcium entry associated regulatory factor.
    
 
 0.428
LOC100553538
Uncharacterized protein.
      
 0.418
LOC100553739
Uncharacterized protein.
      
 0.418
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.