Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MMS19MMS19 homolog, cytosolic iron-sulfur assembly component. (958 aa)    
Predicted Functional Partners:
CIAO2B
Cytosolic iron-sulfur assembly component 2B.
    
 0.998
CIAO3
Cytosolic iron-sulfur assembly component 3; Belongs to the NARF family.
    
 0.982
FBXL5
F-box and leucine rich repeat protein 5.
    
 
 0.966
CDKAL1
CDK5 regulatory subunit associated protein 1 like 1.
   
 
 0.953
POLD1
DNA polymerase.
   
 0.951
POLE
DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.
   
 0.949
PPAT
Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
    
 
 0.948
DNA2
DNA replication helicase/nuclease 2.
    
 0.942
PRIM2
DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.
    
 
 0.936
CIAO2A
Cytosolic iron-sulfur assembly component 2A.
    
 0.929
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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