STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMS19MMS19 homolog, cytosolic iron-sulfur assembly component. (958 aa)    
Predicted Functional Partners:
CIAO2B
Cytosolic iron-sulfur assembly component 2B.
    
 0.992
CIAO2A
Cytosolic iron-sulfur assembly component 2A.
    
 0.967
CIAO3
Cytosolic iron-sulfur assembly component 3; Belongs to the NARF family.
    
 0.852
brip1
HELICc2 domain-containing protein.
    
 0.813
rtel1
Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...]
    
 0.813
DDX11
DEAD/H-box helicase 11.
    
 0.808
POLE
DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.
    
 0.780
ERCC3
ERCC excision repair 3, TFIIH core complex helicase subunit.
   
 
 0.772
POLD1
DNA polymerase.
    
 0.772
DNA2
DNA replication helicase/nuclease 2.
    
 0.769
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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