STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LYSTLysosomal trafficking regulator. (3762 aa)    
Predicted Functional Partners:
VPS18
VPS18 core subunit of CORVET and HOPS complexes.
   
  
 0.695
vps11
Uncharacterized protein.
   
  
 0.684
NOLC1
Nucleolar and coiled-body phosphoprotein 1.
      
 0.640
VPS39
VPS39 subunit of HOPS complex.
      
 0.605
VTA1
Vesicle trafficking 1.
    
 
 0.587
RACK1
Receptor for activated C kinase 1.
    
 0.561
LAMP1
Lysosomal associated membrane protein 1.
   
 
 0.558
SMPD2
Sphingomyelin phosphodiesterase 2.
     
 0.536
UNC13D
Unc-13 homolog D.
   
  
 0.533
LOC100556341
Death domain-containing protein.
    
 0.521
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.