Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SORBS2Sorbin and SH3 domain containing 2. (1210 aa)    
Predicted Functional Partners:
VCL
Vinculin.
   
 0.850
PDLIM5
PDZ and LIM domain 5.
   
 0.700
COPS7A
COP9 signalosome subunit 7A.
      
 0.697
ABL2
Tyrosine-protein kinase.
    
  0.633
ABL1
Tyrosine-protein kinase.
    
  0.633
sorl1
Uncharacterized protein.
    
 0.616
VTA1
Vesicle trafficking 1.
    
 
 0.611
GCH1
GTP_cyclohydroI domain-containing protein.
    
   0.609
WASF1
WASP family member 1.
    
 0.603
TLCD5
TLC domain containing 5.
      
 0.596
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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