Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
KCNK17Potassium channel subfamily K member. (316 aa)    
Predicted Functional Partners:
KCNJ15
Potassium voltage-gated channel subfamily J member 15.
      
 0.787
kcnk18
Uncharacterized protein; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
     
 0.719
KCTD18
Potassium channel tetramerization domain containing 18.
      
 0.702
KCNMB1
Potassium calcium-activated channel subfamily M regulatory beta subunit 1.
      
 0.694
KCNK16
Potassium two pore domain channel subfamily K member 16; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
     
 0.662
LOC100556850
Uncharacterized protein; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
     
 0.662
MARCHF10
Membrane associated ring-CH-type finger 10.
      
 0.612
CCDC189
Uncharacterized protein.
      
 0.610
CFAP100
Cilia and flagella associated protein 100.
      
 0.610
GNG8
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
      
 0.599
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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