STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IGFBP7Insulin like growth factor binding protein 7. (117 aa)    
Predicted Functional Partners:
FREM1
FRAS1 related extracellular matrix 1.
      
 0.686
LOC100561497
C-type lectin domain-containing protein.
      
 0.686
ins
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
    
 
 0.563
IGF2
Insulin like growth factor 2.
    
 
 0.545
hus1
Checkpoint protein; Belongs to the HUS1 family.
      
 0.506
RHOQ
Ras homolog family member Q.
      
 0.489
SLC22A3
Solute carrier family 22 member 3.
      
 0.429
azin1
Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
      
 0.425
GABRA3
Gamma-aminobutyric acid type A receptor alpha3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
      
 0.422
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
Server load: low (16%) [HD]