STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)    
Predicted Functional Partners:
PDPK1
3-phosphoinositide dependent protein kinase 1.
  
0.987
TSC1
TSC complex subunit 1.
    
 0.976
MDM2
MDM2 proto-oncogene.
    
 0.976
MTOR
Serine/threonine-protein kinase TOR.
    
 0.974
FOXO6
Forkhead box O6.
    
 0.973
FOXO1
Forkhead box O1.
    
 0.973
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
   
0.972
TSC2
TSC complex subunit 2.
    
 0.967
CASP9
Caspase 9; Belongs to the peptidase C14A family.
    
 0.963
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
   
0.961
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.