STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NRASNRAS proto-oncogene, GTPase. (194 aa)    
Predicted Functional Partners:
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
   
 0.978
RASA1
RAS p21 protein activator 1.
   
 0.969
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
   
 0.968
ARAF
A-Raf proto-oncogene, serine/threonine kinase.
   
 0.964
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
   
 0.964
KIT
KIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
 0.959
SOS2
SOS Ras/Rho guanine nucleotide exchange factor 2.
   
 0.955
RAPGEF2
Rap guanine nucleotide exchange factor 2.
   
 0.945
RASSF5
Ras association domain family member 5.
    
 0.944
RASA2
RAS p21 protein activator 2.
    
 0.942
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.