STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRB7Growth factor receptor bound protein 7. (588 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
    
 0.764
IGF1R
Tyrosine-protein kinase receptor.
    
 0.598
INSRR
Tyrosine-protein kinase receptor.
    
 0.598
VAV2
Vav guanine nucleotide exchange factor 2.
   
 
 0.587
PTPRF
Protein tyrosine phosphatase receptor type F.
   
 0.559
PTPN6
Protein tyrosine phosphatase non-receptor type 6.
    
 0.558
RET
Ret proto-oncogene; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.535
ins
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
     
 0.502
GRAP2
GRB2 related adaptor protein 2.
    
 0.490
EPHB4
EPH receptor B4.
    
 0.486
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.