STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HEPHHephaestin; Belongs to the multicopper oxidase family. (1165 aa)    
Predicted Functional Partners:
SLC40A1
Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
    
 0.674
ATP7A
ATPase copper transporting alpha.
  
 
 0.495
ATP7B
ATPase copper transporting beta.
  
 
 0.495
LOC103282880
PX domain-containing protein.
      
 0.469
PROS1
Protein S.
   
 0.466
PLD1
Phospholipase.
      
 0.462
AASDH
Aminoadipate-semialdehyde dehydrogenase.
     
 0.450
DST
Dystonin.
   
  
 0.442
ITSN2
Intersectin 2.
      
 0.430
PLAA
Phospholipase A2 activating protein.
      
 0.428
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.