STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CISD1CDGSH iron sulfur domain 1. (108 aa)    
Predicted Functional Partners:
DDB1
Damage specific DNA binding protein 1.
    
 
 0.772
cisd3
Uncharacterized protein.
   
  
 0.732
DDA1
DET1 and DDB1 associated 1.
    
 
 0.613
TOMM70
Translocase of outer mitochondrial membrane 70.
      
 0.561
CARS2
Cysteinyl-tRNA synthetase 2, mitochondrial.
      
 0.456
AASDH
Aminoadipate-semialdehyde dehydrogenase.
      
 0.434
ISCA2
Iron-sulfur cluster assembly 2.
    
 
 0.426
CCDC58
Coiled-coil domain containing 58.
   
  
 0.422
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.