node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADA | ADA2 | ENSACAP00000016622 | ENSACAP00000012034 | Adenosine deaminase. | Adenosine deaminase 2. | 0.955 |
ADA | DTYMK | ENSACAP00000016622 | ENSACAP00000000660 | Adenosine deaminase. | Deoxythymidylate kinase. | 0.442 |
ADA | IMPDH1 | ENSACAP00000016622 | ENSACAP00000000414 | Adenosine deaminase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.543 |
ADA | LOC100563682 | ENSACAP00000016622 | ENSACAP00000007989 | Adenosine deaminase. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.965 |
ADA | NT5M | ENSACAP00000016622 | ENSACAP00000004363 | Adenosine deaminase. | 5',3'-nucleotidase, mitochondrial. | 0.935 |
ADA | UPP2 | ENSACAP00000016622 | ENSACAP00000007387 | Adenosine deaminase. | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. | 0.528 |
ADA | pnp | ENSACAP00000016622 | ENSACAP00000007893 | Adenosine deaminase. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.965 |
ADA2 | ADA | ENSACAP00000012034 | ENSACAP00000016622 | Adenosine deaminase 2. | Adenosine deaminase. | 0.955 |
ADA2 | LOC100563682 | ENSACAP00000012034 | ENSACAP00000007989 | Adenosine deaminase 2. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.951 |
ADA2 | NT5M | ENSACAP00000012034 | ENSACAP00000004363 | Adenosine deaminase 2. | 5',3'-nucleotidase, mitochondrial. | 0.935 |
ADA2 | UPP2 | ENSACAP00000012034 | ENSACAP00000007387 | Adenosine deaminase 2. | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. | 0.528 |
ADA2 | pnp | ENSACAP00000012034 | ENSACAP00000007893 | Adenosine deaminase 2. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.951 |
DTYMK | ADA | ENSACAP00000000660 | ENSACAP00000016622 | Deoxythymidylate kinase. | Adenosine deaminase. | 0.442 |
DTYMK | NT5M | ENSACAP00000000660 | ENSACAP00000004363 | Deoxythymidylate kinase. | 5',3'-nucleotidase, mitochondrial. | 0.925 |
DTYMK | UPP2 | ENSACAP00000000660 | ENSACAP00000007387 | Deoxythymidylate kinase. | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. | 0.563 |
GMPR | GMPR2 | ENSACAP00000003800 | ENSACAP00000003962 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.901 |
GMPR | IMPDH1 | ENSACAP00000003800 | ENSACAP00000000414 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.917 |
GMPR | LOC100563682 | ENSACAP00000003800 | ENSACAP00000007989 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.445 |
GMPR | NT5M | ENSACAP00000003800 | ENSACAP00000004363 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 5',3'-nucleotidase, mitochondrial. | 0.933 |
GMPR | pnp | ENSACAP00000003800 | ENSACAP00000007893 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.445 |