STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANXA11Annexin. (504 aa)    
Predicted Functional Partners:
CD63
Tetraspanin.
   
  
 0.656
PLG
Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]
     
 0.607
TSG101
Tumor susceptibility 101.
   
 
 0.580
LOC100552932
CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family.
      
 0.570
BCL2
BCL2 apoptosis regulator.
   
  
 0.544
GAPDH
Glyceraldehyde-3-phosphate dehydrogenase.
      
 0.502
SRI
Sorcin.
   
 0.498
CACYBP
Calcyclin binding protein.
      
 0.484
ALG2
ALG2 alpha-1,3/1,6-mannosyltransferase.
    
 
 0.477
CD81
Tetraspanin.
   
  
 0.477
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.