STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DKK3Dickkopf WNT signaling pathway inhibitor 3. (351 aa)    
Predicted Functional Partners:
dkk2
Dickkopf_N domain-containing protein.
      
 0.746
AXIN2
Axin 2.
      
 0.688
EDAR
Ectodysplasin A receptor.
      
 0.688
TCF7
Transcription factor 7.
      
 0.688
LEF1
Lymphoid enhancer binding factor 1.
      
 0.688
DKK1
Dickkopf WNT signaling pathway inhibitor 1.
      
 0.673
LOC100560601
Insulin like growth factor binding protein 5.
   
  
 0.647
SFRP2
Secreted frizzled related protein 2.
     
 0.624
LGR5
Leucine rich repeat containing G protein-coupled receptor 5.
     
 0.623
IRX2
Iroquois homeobox 2.
    
 
 0.620
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.