STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptpn18Uncharacterized protein. (546 aa)    
Predicted Functional Partners:
CSK
Tyrosine-protein kinase.
   
 0.777
SHC1
SHC adaptor protein 1.
   
 0.700
PTPN12
Protein tyrosine phosphatase non-receptor type 12.
 
   
  0.689
PSTPIP1
Proline-serine-threonine phosphatase interacting protein 1.
   
 
 0.642
ARHGEF4
Rho guanine nucleotide exchange factor 4.
      
 0.544
CD247
CD247 molecule.
   
 0.498
blk
Tyrosine-protein kinase.
   
 0.489
H9GSE5_ANOCA
Alpha-carbonic anhydrase domain-containing protein; Belongs to the alpha-carbonic anhydrase family.
 
  
   0.480
PSTPIP2
Proline-serine-threonine phosphatase interacting protein 2.
   
 
 0.474
CD3E
CD3e molecule.
   
 0.449
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.