STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ESPL1Extra spindle pole bodies like 1, separase. (2218 aa)    
Predicted Functional Partners:
pttg1
Uncharacterized protein.
   
 0.999
RAD21
RAD21 cohesin complex component.
   
 0.991
SMC3
Structural maintenance of chromosomes protein.
   
 0.987
RANBP2
RAN binding protein 2.
   
 
 0.983
PLK1
Polo like kinase 1.
   
 0.977
SMC1A
Structural maintenance of chromosomes protein.
   
 0.976
SMC1B
Structural maintenance of chromosomes protein.
   
 0.976
rec8
Rad21_Rec8 domain-containing protein.
   
 0.974
bub1b
BUB1 N-terminal domain-containing protein.
   
 
 0.973
KIF11
Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
  
 
 0.967
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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