STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100562324SH3 domain-containing protein. (574 aa)    
Predicted Functional Partners:
ACTR2
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
   
 0.947
WAS
WASP actin nucleation promoting factor.
   
 0.936
TJP1
Tight junction protein 1; Belongs to the MAGUK family.
    
 0.934
ACTR3
Actin related protein 3; Belongs to the actin family.
   
 0.929
actr3b
Uncharacterized protein; Belongs to the actin family.
   
 0.929
actg1
Actin gamma 1.
    
 0.920
WHAMM
WASP homolog associated with actin, golgi membranes and microtubules.
   
 0.911
H9GHP5_ANOCA
Uncharacterized protein.
   
 0.737
STX5
Syntaxin 5; Belongs to the syntaxin family.
    
 0.726
USO1
USO1 vesicle transport factor.
   
 0.697
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.