KPNB1 protein (Anolis carolinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

KPNB1

Karyopherin subunit beta 1. (876 aa)

Predicted Functional Partners:

RAN

0.998

RANBP2

0.996

SNUPN

0.990

KPNA1

0.986

NUP153

0.961

DKC1

0.952

KPNA2

0.948

KPNA5

0.939

LOC100552817

0.898

PTHLH

0.898

Your Current Organism:

Anolis carolinensis

NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DKC1	KPNB1	ENSACAP00000015380	ENSACAP00000007072	Dyskerin pseudouridine synthase 1.	Karyopherin subunit beta 1.	0.952
KPNA1	KPNA2	ENSACAP00000006427	ENSACAP00000000380	Karyopherin subunit alpha 1.	Importin subunit alpha; Belongs to the importin alpha family.	0.495
KPNA1	KPNA5	ENSACAP00000006427	ENSACAP00000013881	Karyopherin subunit alpha 1.	Importin subunit alpha; Belongs to the importin alpha family.	0.590
KPNA1	KPNB1	ENSACAP00000006427	ENSACAP00000007072	Karyopherin subunit alpha 1.	Karyopherin subunit beta 1.	0.986
KPNA1	NUP153	ENSACAP00000006427	ENSACAP00000004070	Karyopherin subunit alpha 1.	Nucleoporin 153.	0.566
KPNA1	RAN	ENSACAP00000006427	ENSACAP00000007043	Karyopherin subunit alpha 1.	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.723
KPNA1	RANBP2	ENSACAP00000006427	ENSACAP00000002048	Karyopherin subunit alpha 1.	RAN binding protein 2.	0.659
KPNA2	KPNA1	ENSACAP00000000380	ENSACAP00000006427	Importin subunit alpha; Belongs to the importin alpha family.	Karyopherin subunit alpha 1.	0.495
KPNA2	KPNB1	ENSACAP00000000380	ENSACAP00000007072	Importin subunit alpha; Belongs to the importin alpha family.	Karyopherin subunit beta 1.	0.948
KPNA2	NUP153	ENSACAP00000000380	ENSACAP00000004070	Importin subunit alpha; Belongs to the importin alpha family.	Nucleoporin 153.	0.588
KPNA2	RAN	ENSACAP00000000380	ENSACAP00000007043	Importin subunit alpha; Belongs to the importin alpha family.	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.724
KPNA2	RANBP2	ENSACAP00000000380	ENSACAP00000002048	Importin subunit alpha; Belongs to the importin alpha family.	RAN binding protein 2.	0.659
KPNA5	KPNA1	ENSACAP00000013881	ENSACAP00000006427	Importin subunit alpha; Belongs to the importin alpha family.	Karyopherin subunit alpha 1.	0.590
KPNA5	KPNB1	ENSACAP00000013881	ENSACAP00000007072	Importin subunit alpha; Belongs to the importin alpha family.	Karyopherin subunit beta 1.	0.939
KPNA5	NUP153	ENSACAP00000013881	ENSACAP00000004070	Importin subunit alpha; Belongs to the importin alpha family.	Nucleoporin 153.	0.568
KPNA5	RAN	ENSACAP00000013881	ENSACAP00000007043	Importin subunit alpha; Belongs to the importin alpha family.	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.585
KPNA5	RANBP2	ENSACAP00000013881	ENSACAP00000002048	Importin subunit alpha; Belongs to the importin alpha family.	RAN binding protein 2.	0.659
KPNB1	DKC1	ENSACAP00000007072	ENSACAP00000015380	Karyopherin subunit beta 1.	Dyskerin pseudouridine synthase 1.	0.952
KPNB1	KPNA1	ENSACAP00000007072	ENSACAP00000006427	Karyopherin subunit beta 1.	Karyopherin subunit alpha 1.	0.986
KPNB1	KPNA2	ENSACAP00000007072	ENSACAP00000000380	Karyopherin subunit beta 1.	Importin subunit alpha; Belongs to the importin alpha family.	0.948