STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OTPOrthopedia homeobox. (192 aa)    
Predicted Functional Partners:
SIM1
SIM bHLH transcription factor 1.
   
  
 0.738
LHX5
LIM homeobox 5.
   
  
 0.606
trh
Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
      
 0.541
SIX3
SIX homeobox 3.
      
 0.522
TBR1
T-box brain transcription factor 1.
    
 0.512
Lhx6
Homeobox domain-containing protein.
      
 0.508
FOXG1
Forkhead box G1.
   
 0.504
TH
Tyrosine hydroxylase.
      
 0.470
LHX9
LIM homeobox 9.
      
 0.466
SHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
   
 
 0.451
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.