STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HIGD1BHIG1 hypoxia inducible domain family member 1B. (92 aa)    
Predicted Functional Partners:
COX6A1
Cytochrome c oxidase subunit 6A, mitochondrial.
   
 
 0.806
COX5B
Cytochrome c oxidase subunit 5B.
   
 
 0.766
COX3
Cytochrome c oxidase subunit 3; Subunits I, II and III form the functional core of the enzyme complex.
    
 
 0.747
COX2
Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.
    
 
 0.737
Ina
IF rod domain-containing protein; Belongs to the intermediate filament family.
      
 0.659
FAM187A
Family with sequence similarity 187 member A.
      
 0.556
UQCRC1
Ubiquinol-cytochrome c reductase core protein 1.
   
 
 0.504
PMPCB
Peptidase, mitochondrial processing beta subunit; Belongs to the peptidase M16 family.
   
 
 0.504
COA6
Cytochrome c oxidase assembly factor 6.
   
 
 0.498
TRIR
Telomerase RNA component interacting RNase.
   
 
 0.498
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.