STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IKZF1IKAROS family zinc finger 1. (585 aa)    
Predicted Functional Partners:
CRBN
Cereblon.
    
 
 0.972
DDB1
Damage specific DNA binding protein 1.
    
 0.780
IKZF3
IKAROS family zinc finger 3.
   
 
0.658
PTPRC
Protein tyrosine phosphatase receptor type C.
   
 
 0.640
GATA1
GATA binding protein 1.
    
 0.589
GATA3
GATA binding protein 3.
   
 0.565
RUNX3
Runt-related transcription factor.
   
 0.553
SPI1
Spi-1 proto-oncogene.
   
 
 0.546
IL7R
Interleukin 7 receptor.
   
  
 0.536
ETV6
ETS variant 6.
    
 
 0.495
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.