STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CTSKCathepsin K; Belongs to the peptidase C1 family. (289 aa)    
Predicted Functional Partners:
Bid
BH3-interacting domain death agonist; Counters the protective effect of Bcl-2.
   
 
 0.911
BCL2L1
BCL2 like 1.
     
 0.903
TLR4
Toll like receptor 4; Belongs to the Toll-like receptor family.
   
 
 0.734
MYD88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 
 0.701
TRAF3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
  
 0.694
CASP9
Caspase 9; Belongs to the peptidase C14A family.
   
 
 0.690
birc2
Uncharacterized protein.
   
 
 0.668
XIAP
X-linked inhibitor of apoptosis.
     
 0.660
BIRC5
Baculoviral IAP repeat containing 5.
     
 0.658
LOC100561388
Uncharacterized protein.
     
 0.658
Your Current Organism:
Anolis carolinensis
NCBI taxonomy Id: 28377
Other names: A. carolinensis, Carolina anole, UCMZ 53793, green anole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.